Hepatic veno-occlusive disease as a presentation of antiphospholipid antibody syndrome in a young kuwaiti woman

A young Kuwaiti woman presented with severe jaundice, constitutional symptoms and deranged liver function tests suggestive of hepatitis. Investigations, including a liver biopsy, showed the presence of hepatic veno-occlusive disease [HVOD] associated with antiphospholipid antibody syndrome [APS]. Clinical and laboratory abnormalities improved rapidly with anticoagulation treatment with warfarin. During the follow-up of over 1 year she remained completely normal without recurrence of symptoms. HVOD is a known but rare presentation of APS. Recognition and treatment of this condition at an early stage can be rewarding